Creatinine Production, Nutrition, and Glomerular Filtration Rate Estimation

Creatinine production, nutrition, and glomerular filtration rate estimation.

This study examined the validity and clinical implications of the assumption of the Modification of Diet in Renal Disease Study (MDRD) formula that age, gender, race, and BUN account for creatinine production (CP). The relationships of MDRD GFR, CP, and nutrition were examined in 1074 Dialysis Morbidity and Mortality Study Wave II patients with reported measured creatinine clearances at initiat...

Estimation of glomerular filtration rate from height/plasma creatinine ratio.

Estimation of glomerular filtration rate from the serum creatinine concentration.

In patients with renal failure the dose of renally excreted drugs should be reduced in proportion with the degree of impairment of glomerular filtration: in this situation it is appropriate to measure the glomerular filtration rate in order to determine accurately the correct dose. However, as 24 hour urine based creatinine clearance measurements are time consuming and inaccurate, the parameter...

Glomerular filtration rate determination by creatinine and cystatin-C in patients with acute pyelonephritis

Background: Measurement of glomerular filtration rate (GFR) and monitoring of it in any patient on nephrotoxic drugs is very important. Recently, cystatin C (cys-C) has been introduced as a better marker for determining and monitoring renal function than creatinine especially in a mild decrease of GFR. This study was done to assess the change of GFR measurement based on serum Cys-C and creatini...

Serum creatinine and glomerular filtration rate: perception and reality.

Na primeira leitura, o relato de Spanaus et al.(13) no Clinical Chemistry pode ser descartado como apenas mais uma comparação entre biomarcadores séricos para taxa de filtração glomerular (TFG). Entretanto, os resultados e as conclusões deverão estimular uma reavaliação da concepção errônea, amplamente disseminada, de que a creatinina sérica é um biomarcador insensível da TFG e uma afirmação do...